Abstract 9254: Race Differences in Ventricular Remodeling Among College Football Players: Implications for a Cardiovascular Screening Program
Objective: Intensive athletic training is associated with increased cardiac ventricular mass and volume. We sought to investigate the hypothesis that African American (AA) football players remodel with a greater mass-to-volume (M:V) ratio than their Caucasian counterparts. We also sought to compare diastolic and systolic function between the two groups. We finally examined the correlation between precordial ECG voltage and M:V ratio.
Methods: All entering Stanford Division I football players (81 Caucasian and 39 AA) over a 5 year period underwent cardiovascular screening with history, physical exam, ECG and focused echocardiogram. Comparison of remodeling and functional indices plus ECG voltage parameters was performed using Student’s t-test and multivariable logistic regression analysis adjusted for body size, resting blood pressure and field position.
Results: Compared with their Caucasian counterparts, AA football players had on average higher LV mass index (77 ± 11 vs. 71±11 g/m2, p=0.009), higher relative wall thickness (0.31 ± 0.04 vs. 0.24 ± 0.20, p<0.001) and higher mass to volume ratio (1.18 ± 0.16 vs. 1.06 ± 0.09 g/mL, p< 0.001). AA football players had lower early diastolic tissue Doppler velocity (18 ± 2 vs. 19 ± 2 cm/s, p=0.043). There were no significant differences in systolic indices of LV ejection fraction or velocity of circumferential shortening. AA players showed significantly greater precordial voltage on QRS spatial vector magnitude score consisting of |V2-S| + |V5-R| (31.9 vs. 27.0 mV, p = 0.002). There were no significant relationships between M:V and net voltage.
Conclusion: College footballers of African ancestry exhibit more physiologic concentric ventricular remodeling, lower early diastolic annular velocities and increased ventricular voltage when compared to Caucasian FP. These findings may be important in deriving race specific indices of ventricular remodeling for use in screening college athletes.
- © 2012 by American Heart Association, Inc.