Abstract 241: Neurocognitive Functioning and Quality of Life After Successful Resuscitation from Cardiac Arrest
Objective Neurocognitive function (NCF) and Quality of Life (QoL) of patients (pts) with an out-of-hospital cardiac arrest (OHCA) may have improved since an increasing number of pts are managed with an AED and Therapeutic Hypothermia (TH) is universally applied. We studied the NCF and QoL of consecutive pts 6-12 months after OHCA and the QoL of their relatives.
Materials and methods The study population comprises all consecutive pts (>18 year) who survived 6-12 months after OHCA from mid-2010 to mid-2011. Pts and relatives were interviewed by telephone. The questionnaires used were validated for telephonic application with a validated cut-off score. The QoL was measured with the SF-12, NCF with the Telephonic Interview Cognitive Status (TICS), level of independence with the Modified Rankin Scale (MRS). If needed, the IQ-code was used as proxy-questionnaire to measure the NCF of the pt. The Caregiver Strain Index (CSI) was used to measure QoL of the relatives. The elderly (≥ 80 years) were compared to an open Dutch population of ≥ 80 years. Treatment effect was calculated with an effect size θ. Effect sizes near 0 are small, >0.8 or <-0.8 are considered as significant and relevant.
Results The proportion of the pts who scored normal on the questionnaires is shown in the table. When TICS and IQ-code are added up, 180 of 220 pts (82%) had a normal NCF. The mean score of elderly on the mental SF-12 was 40.5 and on the physical SF-12 53.2, while the compatible population scored 38.1 (θ =-0.20) and 54.4 (θ =0.15), respectively. Pts with TH scored 54.2 on the mental SF-12, while pts without TH scored 52 (θ=0.26). The mean score on the physical SF-12 of pts with TH was 46.4 and without the need of TH 44.8 (θ=0.16), respectively.
Conclusion QoL, NCF and independency in daily-life 6-12 months after OHCA is normal in the great majority of pts. Mental QoL is better compared to physical QoL. Pts ≥80 years score equal to age comparable persons of the normal population. Outcome after TH is equal to those not needing TH.
- © 2012 by American Heart Association, Inc.