Abstract 18164: The Effectiveness of Chronic Total Occlusion Recanalization is Still Questionable
Background: Chronic total occlusion (CTO) recanalizations remain extremely challenging procedures. With improvements in technology and techniques, success rates for recanalization of CTO continue to improve. However, the clinical benefits of this practice remain unclear. The aim of the study was to determine the effectiveness of CTO recanalization on clinical outcomes.
Methods: It was a multicenter, prospective observational study conducted in Korea, from Jan 2007 to Dec 2009. 3174 consecutive patients with CTO undergoing PCI were included in the study. We selected a total of 2578 patients with available medical records and the patients were grouped as follows: group 1; 2045 patients with successful recanlization and group 2; 480 patients with failed PCI. Patients were assessed long term clinical outcomes including death and myocardial infarction (MI).
Results: Patients in group 2 were older (62.5 ± 11.0 vs. 64.0 ± 9.8, p-value: 0.002) and had more medical histories such as history of MI or PCI. But other baseline characteristics were similar in both groups. Median follow up duration were 729 days (interquartile range: 650, 757). There is no significant difference in 2-year mortality rates (2.7% vs. 2.2%, p-value: 0.636) and composite of death or MI rates (3.0% vs. 2.5%, p-value: 0.519) between two groups
Conclusions: In this retrospective study, we failed to prove the beneficial effect of successful recanlizations to improve clinical outcomes. However, randomized clinical trials are needed to confirm these findings.
- © 2012 by American Heart Association, Inc.