Abstract 17910: Comparison of Outcomes Following Percutaneous Coronary Intervention in Indo-Canadian and non Indo-Canadian Patients
OBJECTIVE: Indo-Canadians (IC) have a higher incidence of coronary artery disease (CAD) than non Indo-Canadians (NIC). Further, evidence suggests IC fare worse after coronary artery bypass grafting (CABG). This study aimed to examine outcomes following PCI among IC patients compared with NIC patients.
METHODS: We examined data from a prospective, province-wide registry of all patients who underwent PCI in British Columbia from April 1, 2004 through December 31, 2010 with links to provincial mortality data. Patients with prior PCI or CABG were excluded. Ethnicity was established using surname analysis methodology. The primary endpoints were 30-day mortality and repeat revascularization (PCI or CABG) during the study period. Predictors of these outcomes were modeled using logistic regression, adjusting for traditional coronary risk factors, number of vessels requiring PCI and other relevant clinical factors.
RESULTS: A total of 65,811 patients, of which 2,611 (4.0%) were IC underwent PCI as a first revascularization. There was no difference in 30-day mortality between IC and NIC (2.1% vs. 2.2%, p=0.75). Incidence of repeat revascularization was higher in IC patients versus NIC patients (23.4% vs. 19.6%, p<.001). The difference in revascularization between IC and NIC was greatest in men (25.3% vs. 20.3%, p<.001). Adjusted analysis revealed that ethnicity was no longer predictive of repeat revascularization (OR, 0.82; 95% CI: 0.64-1.05), though several other clinical and sociodemographic variables were.
CONCLUSIONS: Indo-Canadians had a higher incidence of repeat revascularization following PCI, though not statistically significant after adjustment for other traditional factors. Traditional cardiac risk factors are more prevalent among IC than NIC, likely explaining the higher incidence of repeat revascularization. Further examination of incidence of target vessel revascularization and long-term mortality is needed.
- © 2012 by American Heart Association, Inc.