Abstract 15206: Prognostic Value of Left Atrial Appendage Function for Maintenance of Sinus Rhythm After Catheter Ablation in Atrial Fibrillation
Purpose: We evaluated whether the left atrial appendage (LAA) function was associated with the prognosis after catheter ablation in the patients with atrial fibrillation (AF).
Method: Transesophageal echocardiography (TEE) and transthoarcic echocardiography (TTE) were performed in 40 patients with nonparoxysmal AF before initial catheter ablation. Using TEE, LAA emptying flow velocity and filling flow velocity were measured by pulsed-wave Doppler echocardiography, and LAA wall motion velocity (LAAWV) were measured by tissue Doppler imaging (TDI). LA diameter, LA volume, LA ejection fraction (LAEF), and wall motion velocity of LA free wall by TDI (LAWV) were measured using TTE. Recurrence of AF was determined over six months after catheter ablation.
Results: In the follow up period, 13 patients had recurrence of AF (Group A) and 27 patients maintained sinus rhythm (Group B). LAA emptying flow velocity and LAAWV were significantly decreased in Group A as compared with Group B (18.2±6.0 vs 27.5±13.8 cm/sec, P<0.05 ; 8.2 ± 3.4 cm/sec vs 12.1 ± 3.0 cm/sec, P<0.01). LAA filling flow velocity and LAWV in the Group A were slower in Group A than Group B but not significantly. There were no significant differences in LA diameter, LA volume, and LAEF between Group A and B. Logistic regression analysis for predicting reccurence of AF was constructed and LAAWV was associated with an increased reccurence of AF (relative risk=1.52, 95%CI 1.03-2.25).
Conclusions: LAA function may be a useful predictor for maintenance of sinus rhythm after catheter ablation in the patients with atrial fibrillation.
- © 2012 by American Heart Association, Inc.