Abstract 15071: One-Year Angiographic Follow-Up After Drug-Eluting Stent Cannot Predict Further Target Vessel Failure: 5-Year Observation from J-PMS Registry
Background: The aim of this study was to evaluate the efficacy of routine angiographic follow up (prediction of further target vessel event) within 12 months using J-PMS (multicenter registry for post marketing surveillance of sirolimus-eluting stent; SES) database.
Method and Results: We studied 1665 lesions from 1424 patients who met the following criteria; complete 5-year follow-up and 9 months aniography both presented no marked stenosis (%DS>50%), and there was no event within 1 year after index procedure. We observed the frequency of target lesion revascurarization (TLR) and non-TL TVR (remote from target lesion) during 1-5 years, and compared the characteristics of TLR before (0-1 year) and after 1 year (late catch-up: 1-5 year from index). The characteristics seen in late catch-up when compared with non-TLR (non-late catch-up) were high frequency of previous PCI (70.1% vs 54.7%, P=0.016), previous CABG (14.9% vs 6.9%, P=0.025), restenotic-location (31.4% vs 19.8%, P=0.013), and ostial-location (25.6% and 16.1%, P=0.026). The frequency of revascularization is shown in the table. Both TLR and non-TL TVR occurred similarly, and the accumulated number of revascularization was close to the number of initial one year (0-1 year: TLR 3.7% and non TL-TVR 4.6%).
Conclusion: Routine angiographic follow-up within 1 year would not predict further target vessel event. In particular, history of revascularization, lesions with restenosis and ostial location were seen more frequently in the late catch-up phenomenon.
- © 2012 by American Heart Association, Inc.