Abstract 14830: Left Ventricular Noncompaction: Affected Wall Regions in Respect to LV Function - Data from the German Noncompaction Registry (ALKK)
Objective: Left Ventricular Noncompaction (LVNC) is considered to occur by an arrest of the myocardial compaction process during embryonic endomyocardial morphogenesis. Normally, the trabecular remodelling starts at the base of the heart progressing to the left ventricular apex until LV compaction is completed. So, in case of LVNC it can be assumed that the apical LV regions should be involved primarily. Until now, only limited data on affected wall regions and LV function are available in small numbers of pts.
Methods: By May 31th, the German Noncompaction registry had enrolled a total of 241 pts with NCCM (163 male, age 18 to 87 years, mean age 56.3 yrs) The echocardiographic image data of the patients were analysed in respect to the affected LV wall regions and the LV function (group A, EF >= 50%, n= 78, group B, EF 36-49%, n= 66, group C, EF <= 35%, n= 97).
Results: The involvement of affected wall regions is shown in the table below. In the pts with no verification of apical involvement the apex could not be adequately visualized. Secondly most affected was the lateral wall, especially in the pts with reduced LV function.
Summary: In cases with LVNC different involvement of affected LV myocardial areas in respect to LV function could be observed. LV apical regions were involved in all pts with adequate image quality. Additionally, in pts with reduced LV function the lateral walls were more likely to be affected.
- © 2012 by American Heart Association, Inc.