Abstract 14220: Neointimal Appearance of Late Clinical Event related Lesions after Bare-Metal Stent and Sirolimus-Eluting Stent Implantation Assessed by Optical Coherence Tomography
Background: Late clinical event such as very late stent thrombosis (VLST) and late in-stent restenosis (ISR) after bare-metal stent (BMS) and drug-eluting stent (DES) is an important clinical issue. However, the difference of underlying mechanisms in late clinical event between BMS and DES has not been fully evaluated yet. The aim of the present study was to compare neointimal tissue appearance of these lesions between BMS and sirolimus-eluting stent (SES) by using optical coherence tomography (OCT).
Methods: We examined the neointimal tissue appearance in 34 late clinical event lesions after BMS (n=15) and SES (n=19) implantation by OCT. Late clinical event was defined as VLST and late ISR (>1 year after initial procedure).
Results: Results were shown in the table described below.
Conclusions: In late clinical event lesions, atherosclerotic change such as TCFA formation and carcification within neointima is often demonstrated in BMS than in SES.
- © 2012 by American Heart Association, Inc.