Abstract 13853: Higher CHADS2 Score Associated with Increased Incidence of Stroke After Coronary Artery Bypass Surgery
Background: The CHADS2 is a scoring system commonly used to identify patients with AF who have a high risk of stroke. We hypothesized that this score could also be used to predict the incidence of stroke among patients who undergo isolated CABG.
Method: We identified patients who had undergone isolated CABG at our institution from January 2001 to December 2010. Patients with a history of atrial fibrillation or valvular heart disease were excluded. The CHADS2 score (computed as the sum of 1 each for congestive heart failure or an EF<35%, hypertension, age ≥75 y, and diabetes, and 2 each for TIA and stroke; the range is therefore 0-6) was calculated for each patient. Using SAS statistics software, we examined the frequency of stroke in 3 score intervals (Low: 0-1, Medium: 2-3, and High: 4-6) and the differences in stroke incidence among these groups.
Results: We studied 5985 patients (mean age 64±11 y, 76% male). Stroke occurred in 2.6% (157/5985; mean age 68±11 y, 68% male) of the patients. The incidence of stroke was progressively higher for patients with Low (1.3%), Medium (3.0%), and High (8.0%) CHADS2 scores. The odds of developing stroke were higher in patients with Medium (OR 2.4, 95% CI 1.6-3.6, p<.0001) and High scores (OR 6.8, 95% CI 1.5-2.3, p<.0001) than in patients with Low scores.
Conclusion: CHADS2 score, which is used in daily practice, can be used to identify patients at high risk of stroke after isolated CABG.
- © 2012 by American Heart Association, Inc.