Abstract 13665: Correlation between Right Arterial Pressure and Right Arterial Volume Index in Patients with Pulmonary Hypertension
Background: Pulmonary hypertension (PH) is a life-threatening disease and is characterized by a marked and sustained elevation of pulmonary vascular resistance, leading to an increase in pulmonary artery pressure and ultimately death. In addition, right arterial pressure has been reported to be an independent predictor for outcome in PH patients. However, non-invasive assessment of pulmonary arterial pressure is limited and it is commonly estimated by the presence of inferior vena cava dilation and the degree of inspiratory its collapse by echocardiography.
Hypothesis: Our objective was to test the hypothesis that right atrial volume as assessed by two-dimensional transthoracic echocardiography is correlated to right arterial pressure by hemodynamic measurement in PH patients.
Methods: A total of 35 PH patients with mean pulmonary artery pressure of 35±10mmHg (all≥25mmHg) were recruited in this study. All patients were underwent echocardiography, and right heart catheterization for the measurement of right atrial pressure. Right atrial volume was assessed by the area-length method in apical 4-chamber view, which focused on the entire right ventricle and atrium, and was corrected for body surface area (right atrial volume index).
Results: There was a significant correlation between right atrial volume index and right atrial pressure (p<0.001, r=0.58).
Conclusions: Non-invasively assessed right arterial volume was associated with right atrial pressure by hemodynamic measurement in PH patients. This approach may have the potential to allow for non-invasive follow-up of PH patients.
- © 2012 by American Heart Association, Inc.