Abstract 13646: Quantification of Longitudinal, Radial, and Circumferential Left Ventricular Deformation by 3 Dimensional Speckle Tracking Echocardiography
Background: Three-dimensional speckle tracking echocardiography (3D-STE) is a novel technique to assess left ventricular (LV) regional deformation. The study was designed to validate segmental LV strain measurements by 3D-STE against conventional 2D-STE.
Methods: Twenty consecutive patients (age 70±9 years, EF 56±13%) underwent echocardiography and LV strain measurements to quantify regional LV deformation. LV 3D-STE data were obtained from apical approach at frame rate>25 fps. LV 2D-STE data were obtained from long and short axis views at frame rate 50-80 fps. Regional LV deformation in the long and short axis directions were assessed by segmental longitudinal (LS), radial (RS), and circumferential (CS) strain measurements by 3D-STE and compared to 2D-STE. Statistical analysis was performed using Pearson’s correlation and Bland-Altman.
Results: Out of a total of 320 segments, 281(88%) were analysable by 3D-STE and 291(91%) by 2D-STE. Segments were excluded due to suboptimal tracking or limited image quality. Out of the 3 strain components LS demonstrated the best correlation between 3D-STE and 2D-STE. (LS: r=0.53, mean difference -1.3±5.5, p<0.001; RS: r=0.31, mean difference 0.01± 20.3, p<0.001; CS: r=0.47, mean difference -0.9±6.8, p<0.001).
Conclusions: The novel technique of 3D-STE can quantify regional LV longitudinal, radial, and circumferential deformation with good feasibility and reasonable correlation compared to conventional 2D-STE.
- © 2012 by American Heart Association, Inc.