Abstract 12987: Retinal Arteriolar-Venular Ratio as a Marker of Cardiac Organ Damage in Hypertensive Patients
INTRODUCTION- The early evaluation of target organ damage (TOD) in hypertensive patients is of primary importance and the study of retinal vessels can be helpful.
HYPOTHESIS- The aim of our study was to assess the correlation between retinal vessels diameters, expressed as AVR (arteriolar-venular ratio) and left ventricular hypertrophy (LVH) or remodeling (LVR).
METHODS- In 70 treated hypertensive individuals (40 men, 30 women, mean age 60 +/-14 years) we performed anthropometric parameters measurement; clinical blood pressure (BP) measurement 24h ambulatory BP monitoring; echocardiography at rest and non-mydriatic digital retinography. Following a standard echocardiographic evaluation we subdivided patients with presence of LVH/LVR (A group) and patients without changes in ventricular geometry (B group). We classified LVH and LVR patterns according to the European Society of Echocardiography Guidelines. We than analysed vessels images by a dedicated software able to calculate AVR, index of retinal arteriolar narrowing. Arteriolar caliber was considered normal if AVR > 0.82, reduced if 0.78, highly reduced if < 0.78.
RESULTS- CONCLUSIONS- We observed that AVR is strictly related to left ventricular hypertrophy and remodeling in fact these ventricular patterns correspond to low AVR, depending on reduced calibres. The non-mydriatic digital retinography is a reproducible, non-invasive, reliable technique, able to assess the presence TOD in hypertensive patients and an excellent marker to provide information on early cardiac damage due to hypertension.
- © 2012 by American Heart Association, Inc.