Abstract 12643: Effect of Sleep Apnea on Coronary Plaque Composition of Non-Culprit Lesions in Patients With Acute Myocardial Infarction: An Integrated Backscatter Intravascular Ultrasound Study
Background: Sleep apnea is associated with a higher incidence of cardiovascular events. The present study evaluated the effect of sleep apnea on plaque component of non-culprit lesions in patients with acute myocardial infarction.
Methods: Integrated backscatter intravascular ultrasound (IB-IVUS) was performed in 34 patients who underwent primary percutaneous coronary intervention for acute myocardial infarction. Overnight sleep study was performed using cardiopulmonary monitoring during the hospitalization. Based on apnea-hypopnea index (AHI), patients were classified into the low AHI (<15) group (n=17) and high AHI (≧15) group (n=17).
Results: Table shows IVUS measurements of non-culprit lesions. The high AHI group had more plaque volume and lipid pool in non-culprit lesions compared to the low AHI group.
Conclusion: Moderate or severe sleep apnea is associated with more plaque volume and lipid pool in non-culprit lesions in patients with acute myocardial infarction.
- © 2012 by American Heart Association, Inc.