Abstract 12537: Effect of Statin on Long-term Outcomes of Percutaneous Transluminal Renal Angioplasty in the Patients with Atherosclerotic Renal Artery Stenosis
Introduction: Percutaneous transluminal renal angioplasty (PTRA) has become popular for treating atherosclerotic renal artery stenosis. However, effect of statin treatment after PTRA is uncertain. Hypothesis: We assessed the hypothesis that prognosis after PTRA was improved by statin treatment. The aim of this study is to examine the influence of statin treatment on outcomes in patients who were received PTRA.
Methods: Consecutive 226 patients (age 72±10, male 71%) who were diagnosed as atherosclerotic renal artery stenosis by duplex ultrasound and angiography were enrolled in the study between Aug 1996 and July 2010. Data were collected on clinical outcomes over a mean follow-up period of 1207±822 days. The primary endpoint was defined as the composite of all-cause death, hospitalization of heart failure, and initiation of dialysis.
Results and Conclusions: 88 patients (39%) received statin treatment during follow-up period. According to Kaplan-Meier analysis, the log-rank test showed patients who received statin treatment have a lower event rate than patients without statin (Log-rank test; p=0.011),and percentage with event was reduced by 15% in the patients with statin treatement 5 years after PTRA. In conclusion, statin treatment was associated with a better outcome in patients with atherosclerotic renal artery stenosis who were received PTRA.
- © 2012 by American Heart Association, Inc.