Abstract 117: Association of Age and Sex with Bystander Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest and Outcomes
Backgrounds: Previous studies showed sex differences of outcomes after cardiopulmonary resuscitation (CPR) are influenced many factors not only patients’ backgrounds including age, but also process of care such as prehospital defibrillation. Under the American Heart Association guideline 2005, it is not certain whether the effect of bystander CPR is different between men and women at different age strata.
Methods and Results: From January 1, 2008 through December 31, 2010, we conducted a prospective, population-based, and observational study involving consecutive patients with out-of-hospital cardiac arrest in whom resuscitation was attempted by emergency responders across Japan. A total of 63,138 witnessed cardiac arrest patients were included in the present study and 30,569 (48.4%) had bystander CPR among them. In the patients with bystander CPR, the proportion of patients with return of spontaneous circulation (ROSC) was higher in men than women (men: 21.6%; women: 12.6%). Age-specific and multivariate analyses adjustments with VF/VT and time from collapse to hospital arrival indicated a significant interaction between age and sex such that sex-specific differences in ROSC became progressively worse in women than men with advancing age (Figure). This trend has still observed at one-month survival even statistical significance has not reached any age strata.
Conclusions: The effect of bystander CPR was larger for women than men in the younger age strata, and it became progressively diminish with advancing age.
- © 2012 by American Heart Association, Inc.