Abstract 10703: Does CHADS2 Score Predict Atrial Arrhythmias?
Background: The CHADS2 score provides clinical guidance for defining stroke risk for patients with atrial fibrillation (AF), but the relationship between CHADS2 score and the incidence of AF is not well defined.
Methods: IMPACT is a single-blind trial randomizing patients with either dual-chamber or resynchronization ICDs to use or not use remote monitoring of atrial high rate events (AHRE) to initiate and terminate anticoagulation based on AHRE burden and CHADS2 score. The relationship between CHADS2 score and incidence and burden of AHRE was explored in the initial 2,161 patients observed for 3,166 patient-years, all of whom were blinded to treatment assignment. The AHRE burden was calculated as the percent time in AHRE during all days of observation for patients with CHADS2 scores 1-2, 3-4, and 5-6.
Results: The incidence of AHRE was similar across all groups based on CHADS2 score, with little effect of CHADS2 score on the mean AHRE burden (Table). The figure shows a similar frequency distribution for AHRE burdens across the range of CHADS2 scores.
Conclusions: AHREs are distributed equally across the range of CHADS2 scores, suggesting that the greater stroke risk of patients with higher CHADS2 scores is not related to a higher incidence or burden of AHRE.
- © 2012 by American Heart Association, Inc.