Abstract 10624: Long-term Clinical Outcome After Primary Stenting for Subclavian Artery Disease
Background: Little is known about long-term clinical outcomes after endovascular therapy (EVT) for subclavian artery disease (SCD). The aim of this study was to investigate the long-term clinical outcome after primary stenting for SCD.
Methods: From January 2001 to December 2010, 83 patients (34% female, 69.9±8.6 years old, 86% left subclavian disease) underwent successful primary stenting for de novo SCD. Mean lesion length was 27.9±12.7mm, chronic total occlusion was included in 27%. Outcome measures were primary and secondary patency and all-cause mortality for SCD. Primary patency was defined as treated vessel without restenosis (defined as >2.5 of peak systolic velocity ratio by duplex) and repeat revascularization.Secondary patency was defined as target vessel which subsequently become totally occluded and is reopened by repeat revascularization. Initial success was defined as <30% of residual stenosis without complications. Complication was included that emergency operation, cerebral infarction, myocardial infarction, aortic dissection and rupture, and puncture site troubles, prolonged hospitalization for any reasons.
Result: The mean follow-up interval was 48 (±34) months. Initial success was achieved in 93% and complication rate was 8%. Primary patency at 1- and 3- and 5-year were97%, 91% and 85%, respectively. Secondary patency was100% during follow-up period. On multivariate analysis, female gender (p=0.02), and vertebral artery stenosis (P<0.01), were independent predictors of primary patency. Overall survival rates were 90%, 79%, 68% at 1- and 3-and 5-years. Cardiovascular mortality was 54%, infectious diseases (severe sepsis, pneumonia) mortality was 16%. On multivariate analysis, age (P=0.02), chronickidney disease (P=0.003), dialysis (P=0.004), were independent predictors of all cause mortality.
Conclusion: Primary stenting for SCD was safety and effective for the long-term clinical follow-up periods.
- © 2012 by American Heart Association, Inc.