Letter by Mc Loughlin and Mc Loughlin Regarding Article, “Sweetened Beverage Consumption, Incident Coronary Heart Disease, and Biomarkers of Risk in Men”
To the Editor:
Recently, de Koning et al1 presented an extensive and elegant investigation in which the consumption of sugar-sweetened beverages was associated with an increased risk of coronary heart disease. These results provide new fundamental insights into novel cardiovascular disease risk factors and primary prevention.
However, in Table 2 of their study, the authors reported 902 events of coronary heart disease for a 184 040 person-years value in the Q1 group (lowest quartile for sugar-sweetened beverages consumption), whereas the Q4 group (the top quartile for sugar-sweetened beverages consumption) showed 946 events of coronary heart disease for a 209 424 person-years value. Considering that the person-years value is influenced by the number of years that each member of a study population has been under observation, the incidence of nonfatal and fatal myocardial infarction adjusted by this value may provide an alternative result.
Because of the important public-health implications of these findings, we believe it would be of great interest to inform the cardiovascular events adjusted as mentioned. Likewise, considering that each patient was assigned to both groups (simultaneously to a respective quartile for sugar-sweetened beverages and to artificially sweetened beverages quartile) and that, therefore, total coronary heart disease and total person-years in both groups are equal, a complete flow chart describing the patients who abandoned or changed their original group during the 22-year follow-up period may clarify the results.
Santiago Mc Loughlin
Mario J. Mc Loughlin
Instituto de Investigaciones Cardiológicas (UBA-CONICET)
Buenos Aires, Argentina
- © 2012 American Heart Association, Inc.