Abstract P381: Recruiting Young Adults Into Obesity Trials: Lessons From The Early Trials
Early adulthood is a time of weight gain yet there is a paucity of evidence about how best to prevent weight gain or promote weight loss in this age group. Data from the Coronary Artery Risk Development in Young Adults (CARDIA) study show that young adults (18-40y) gain an average of 1-2 pounds per year with the largest weight gain (about 3 pounds a year) during the ages of 20-29. Excess weight gain in early adulthood is associated with later adverse levels of cardiovascular risk factors such as hypertension, dyslipidemia, and diabetes. To address this issue, in 2009 the National Heart, Lung, and Blood Institute, along with the Eunice Kennedy Shriver National Institute of Child Health and Human Development funded seven separate randomized controlled trials to refine and test behavioral approaches for weight control among young adults (18-35y) at high risk for weight gain. All studies focus on prevention of weight gain or weight loss among young adults, conduct formative research, conduct a two-year randomized controlled trial, and use innovative technologies (e.g.., social media, texting, smart phones). Recruitment issues for health-related interventions in this population group have been recognized as a significant challenge. Recruitment challenges include high mobility, competing demands (school, jobs, young families), low perceived risk of health consequences, and lack of investigator experience targeting this population, Each of the seven EARLY studies tests its own primary hypotheses, with a cumulative estimated sample size of 6063 young adults. To date with the trials approximately half way through the recruitment period, the 7 studies have had an initial contact with 12,669 participants and have screened 6425 participants. After prescreening, screening and the consent procedure, 1554 participants have been randomized, representing about 12% of those initially contacted about the study. The EARLY trials have recruitment targets for males, Hispanic and non-white participants and success with those goals has differed across the seven trials. The objective of this presentation is to present details on prescreening, screening, consent and randomization rates across the trials and to describe the recruitment process for the EARLY trials. We will describe recruitment methods and strategies that have been found to be most effective in recruiting young adults into the EARLY obesity trial. Strategies used to target Hispanic and non-White young adults as well as male participants will also be detailed.
- © 2012 by American Heart Association, Inc.