Abstract P374: Short-term Weight Loss Patterns and Physical and Psychological Predictors within a Randomized Trial
Objective To examine weight loss patterns and their baseline predictors among participants in a Diabetes Prevention Program-based group lifestyle intervention.
Methods Overweight/obese participants in the intensive intervention arm (n=72) of an ongoing 3-arm randomized weight loss trial were weighed at each of 12 weekly classes. Cluster analysis grouped participants with similar patterns of 12-week weight loss. Bivariate analysis identified candidate baseline predictor variables (P<0.1), which were then entered into a stepwise multinomial logistic regression analysis to identify variables significantly associated with greater weight loss patterns.
Results Participants had a mean age of 55.0 yrs (SD 10.8); 49% were female, 79% Non-Hispanic White, and 97% college educated; and 58% earned >$125,000/yr. Mean Body Mass Index was 31.9 kg/m2 (SD 5.2), 56% had pre-diabetes, and 90% had metabolic syndrome. Cluster analysis identified three weight loss patterns (Figure): modest & delayed (G1: n=15; 21%); moderate & steady (G2: 43; 60%); and substantial & early (G3: 14; 19%). Only participants in G2 and G3 had significant weight loss. Candidate predictor variables included sex, physical activity, physical function, family/friend encouragement for dietary change, obesity-related problems, depression symptoms, and body image dissatisfaction. On stepwise logistic analysis comparing G2 and G3 vs. G1, greater weight loss patterns were associated with higher physical activity (standardized β=0.62 (95% CI 0.09, 1.14), P=0.01) and physical function (0.47 (-0.04, 0.99), P=0.05), fewer obesity-related problems (-0.48 (-1.03, 0.07), P=0.09), and less friend encouragement for dietary change (-0.79 (-1.37, -0.22), P=0.003).
Conclusion We identified 12-week weight loss patterns and baseline variables that may be important predictors of response to an evidence-based group lifestyle intervention. Friend encouragement for dietary change may have a more complex relationship to weight loss than suggested by prior research.
Funding(This research has received full or partial funding support from the American Heart Association, National Center)
- © 2012 by American Heart Association, Inc.