Abstract P310: The Distribution of Total- and HDL Cholesterol and Triglycerides is Significantly Different across Quartiles of Vitamin D in Chest-Pain Patients with a Suspected Acute Coronary Syndrome
Background: The purpose of this study was to assess the distribution of serum lipids including total cholesterol, HDL cholesterol and triglycerides across quartiles of vitamin D in blood samples collected from 982 chest-pain patients with a suspected acute coronary syndrome (ACS) from Salta, Northern-Argentina.
Methods: Vitamin D status was obtained by determination of 25-hydroxy-vitamin D (25(OH)D) in serum. Blood samples for measurement of 25(OH)D and circulating lipid fractions in serum were obtained immediately following admission.
Results: In the total population the concentration of total cholesterol, HDL cholesterol and triglycerides was found to differ significantly across quartiles of 25(OH)D, p = 0.016, p = 0.01 and p = 0.000, respectively. See Figure 1, 2 and 3, respectively. In the Troponin T (TnT) positive population (TnT > 0.01 ng/mL), only total cholesterol and triglycerides differed significantly across the 25(OH)D quartiles, p = 0.000 and p = 0.003, respectively, whereas HDL cholesterol alone differed in the TnT negative group, p = 0.025.
Conclusion: Concentrations of the main lipid fractions are related to the vitamin D status in patients admitted with chest pain and suspected ACS.
- © 2012 by American Heart Association, Inc.