Abstract MP077: Dietary Sodium Potassium Ratio as a Risk Factor for Stroke, Cardiovascular Diseases and All-cause Death Among Japanese: Nippondata80.
Objective Japanese have higher intake of sodium and lower intake potassium than Western countries. We evaluated the impact of Sodium potassium ratio on mortality from stroke, cardiovascular diseases (CVD) and all causes using 24 year follow-up data of population randomly selected from Japanese at National cardiovascular Survey in 1980.
Method Participants with age 30 years old or more (n=10536) in the 1980 National Cardiovascular Survey was followed-up for 24 years with a follow-up rate of 92%. We combined individual National Nutrition Survey data conducted for the same participants. Participants without hypertensive treatment and without past histories of stroke and acute myocardial infarction (n = 8982) were divided into quintile according to sodium potassium ratio assessed by 3 day dietary record method at the baseline survey. Observed number of death during follow-up was 1938. Under line causes of death were identified by using Vital Statistics,Japan. Age adjusted and multi-adjusted hazard ratio was calculated using.Cox’s proportional hazard model.
Results Mean intake of Sodium and potassium at the baseline was 242 and 208 mEq, and 77.7 and 70.8 mEq for men and women, respectively. Sodium potassium ratio was significantly related to mortality from stroke, cardio vascular diseases and all causes of death among men and for all adjusting other major risk factors. Multi-adjusted hazard ratio (95% confidence interval) of mortality from all causes, CVD and stroke for both sexes with one quintile of sodium potassium ratio was 1.04(1.01-1.08), 1.08(1.02-1.14) and 1.14 (1.05-1.24). Relationship was still significant after adjusting SBP levels.
Conclusion Sodium potassium ratio was significant risk factor for death from all causes, CVD and stroke among Japanese.
- © 2012 by American Heart Association, Inc.