Letter From van Galen et al Regarding Article, “Cardiac Amyloidosis: A Treatable Disease Often Overlooked”
To the Editor:
Recently, Falk pointed toward the importance of an early diagnosis of cardiac AL (light-chain) amyloidosis (CA) in view of the increasing number of treatment options. Unfortunately, the efficacy of an implantable cardioverter-defibrillator (ICD) to prevent sudden cardiac death (SCD) was considered to be negligible.1 Nevertheless, SCD severely threats CA patients. We fear that, on the basis of scarce literature only, ICD use in CA is becoming a nonissue undeservedly.
From our own clinical practice and a critical review of literature, we believe that selected patients could possibly benefit from an ICD. First, potential SCD was prevented in 2 CA patients, diagnosed at the VU University Medical Center, …