Abstract 8611: The Early Calcification in Neointima of in Stent Restenosis
Background: It has been proven that homogeneous neointima in the early phase after stent implantation transforms into atherosclerotic tissue in their late phase and develops calcification, but there are several cases that demonstrate calcification in the neointima of in stent restenosis (CISR) in their early phase (<=365days).
Purpose: To elucidate the timing, prevalence, and extent of CISR.
Method: The images of intravascular ultrasound (IVUS) taken between 6/30/2009 to 2/28/2011 were analyzed. The patients were divided into two groups depending on the follow up period: (less than 365 days or greater than 365 days)
Result: A total of 169 IVUS images were analyzed. In general, patient with CISR had higher serum creatinine levels (3.3±3.4 mg/dl vs 1.4±1.6 mg/dl; p<0.001) with a higher percentage of hemodialysis patients (36% vs 6%; p<0.0001) and longer follow up time (2136±173 days vs 796±1129 days; p<0.001) than patients without CISR. The patients who developed CISR during the early follow up period (<=365 days) were almost exclusively those on hemodialysis (88%) and accounted for 8.2% of the patients with early follow up period.
Conclusion: The development of CISR within the early follow up period (<=365days) was observed in 8.2% of patients, most of whom required hemodialysis.
- © 2011 by American Heart Association, Inc.