Abstract 8452: Accuracy of 3D Echocardiography on Imaging Ventricular Septal Defect Size: An in vitro Validation Study
Background: Ventricular septal defect (VSD) is one of the most common congenital heart diseases, but the accuracy of defining VSD orifices has not been validated for 3D echo.
Methods: We studied 4 fresh porcine hearts due to their anatomical similarity with human hearts. Each heart was connected to a calibrated pulsatile pump with different stroke volumes (SV, 30-80ml) on the left ventricular (LV) side and constant 40ml on the right ventricular (RV) side through a balloon VSD model, secured in LV and RV, that contained a tube of various size to define the VSD orifice (0.700cm, 1.00cm, 1.25cm, 1.59cm in diameter). Each heart was mounted in a water bath to facilitate ultrasound scanning and driven passively by 2 pumps at a constant rate of 50bpm. 3D images were gathered on GE Vivid 9, BT10 & BT09 and analyzed by EchoPac PC.
Results: 3D echo detected the VSD orifice, and the size can be measured accurately by the program. The measured orifice sizes increase as SVs increase except SV40. The measured value at SV60 is the closest to the actual orifice size, while the measured value is the smallest at SV40.
Conclusions: 3D echo can accurately measure the VSD orifice size, and the variation of VSD orifice with SV can be explained by mechanism of expanding and contracting of the myocardium surrounding the simulated VSD orifice by difference in stroke volumes of the two chambers.
- © 2011 by American Heart Association, Inc.