Abstract 8438: Sugar-Sweetened Beverage Consumption and Incident Cardiovascular Risk Factors: The Multi-Ethnic Study of Atherosclerosis (MESA)
Introduction: Sugar-sweetened beverage (SSB) consumption has been associated with obesity, dyslipidemia, hypertension and type 2 diabetes (T2D). Data reporting associations between SSB intake and incident cardiovascular (CV) risk factors in large, ethnically diverse prospective cohorts are sparse. OBJECTIVE: To quantify associations between SSB consumption and risk of incident CV risk factors in the Multi-Ethnic Study of Atherosclerosis (MESA).
Methods: SSB consumption was assessed by food frequency questionnaire at baseline (2000-2002) in 4,166 African American, Caucasian, Chinese, and Hispanic adults (45-84 years) without baseline clinical CV disease. Incident CV risk factors were identified at three follow-up exams (2002-2003, 2004-2005, and 2005-2007) and included weight gain (>3% higher than baseline); increased waist circumference (WC) (>3% higher than baseline); low HDL (HDL <40mg/dL [men] <50mg/dL [women), LDL <160mg/dL, and triglycerides (TG) 40mg/dL [men], >50mg/dL [women], LDL 150mg/dL; impaired fasting glucose (IFG) (FG 101-126 mg/dL) and T2D (FG>126 mg/dL or diabetes medication use). Except in T2D analyses, participants with diabetes were excluded and participants on lipid lowering medications were excluded from lipid analyses. Hazard ratios (95% CI) were estimated and adjusted for demographics, intentional exercise, dietary confounders (including energy intake) and baseline traditional CV risk factors. RESULTS: Compared to SSB consumption of <1 serving/day, intake of 2+ servings/day was significantly associated with greater risk for incident increased WC, hypertriglyceridemia and IFG among women; associations which were not observed in men (Figure 1).
Conclusions: The metabolic influence of SSBs is complex and is not homogenous between men and women. Women exhibit lower energy requirements compared to men and therefore experience higher CV risk when a greater proportion of calories is consumed in the form of SSBs.
- © 2011 by American Heart Association, Inc.