Abstract 16175: Effect of Dietary Intake of Kiwi Fruit on 24-Hour Ambulatory Blood Pressure
Objective Kiwi fruit contains lutein, an oxycarotenoid that has antioxidant properties. An increased antioxidant capacity may lower blood pressure (BP) through modulation of nitric oxide mediated vascular reactivity. In the present study we studied the effect of adding kiwi to the usual diet on 24-hour ambulatory BP in mildly hypertensive subjects.
Subjects and methods A total of 50 men and 68 women aged 55 ± 9 years with systolic/diastolic BP 128 ± 14 mmHg/ 85 ± 8 mmHg were randomized to intake of three kiwi fruits (intervention group) or one apple (control group) per day for eight weeks. No other dietary changes were made. Ambulatory BP was measured at randomization and at the end of the study. Results between groups were analyzed using a general linear model with change from baseline to eight weeks as the dependent variable, intervention group as a categorical variable, and with adjustment for the baseline value of the analyzed variable (model 1) or adjustment for BMI, gender, age and the baseline value of the analyzed variable (model 2).
Results After eight weeks, 24-hour ambulatory systolic BP was lower in the group randomized to kiwi versus apple (between group difference, 3.6 mmHg [95% CI 0.7, 6.5], P=0.017 in model 1 and 3.3 mmHg [95% CI 0.4, 6.2], P=0.029 in model 2). Ambulatory diastolic BP was lower in the kiwi group after adjusting for baseline values of the variable (between group difference, 1.9 mmHg [95% CI 0.3, 3.6], P=0.040; model 1), but not when adjusting for all covariates (1.6 mmHg [95% CI -0.2, 3.4], P=0.079; model 2).
Conclusion Three kiwi a day improved 24-hour BP more than an apple a day. Incorporating kiwi intake as part of DASH or other diets for treatment of hypertension should be studied.
- © 2011 by American Heart Association, Inc.