Abstract 15859: Emerging Biomarkers Can Predict Main Pulmonary Artery Involvement in Acute Pulmonary Embolism
Purpose: The aim of the study was to assess the correlation with emerging biomarkers and pulmonary computed tomography(CT) angiography severity.
Method: A total of 104 patients with pulmonary embolism were investigated. Pulmonary CT angiography severity was divided into two groups according to main pulmonary artery involvement . All patients had blood drawn to measure levels of emerging biomarkers before pulmonary CT angiography was performed.
Result: D-dimer (P=0.047), Tn-I (P=0.040) and CK-MB (P=0.033) values was significantly increased according to the main pulmonary artery involvement. Pro-BNP (P=0.018) was significantly increased according to the main pulmonary artery involvement. RV strain pattern in electrocardiogram (P<0.001) was properly appeared according to the main pulmonary artery involvement.
Conclusion: Emerging biomarkers including D-dimer, Tn-I, CK-MB can predict the main pulmonary artery involvement in acute pulmonary embolism. Therefore, D-dimer, Tn-I and CK-MB can be a good predictor of main pulmonary artery involvement in emergency state.
- © 2011 by American Heart Association, Inc.