Abstract 15810: Air Pollution is Associated With Increased Blood Pressure: Results From High-Exposed Individuals in Beijing, China
Background Particulate Matter (PM) air pollution is critical in Beijing, China, due to very high population density, rapid increase in the number of vehicles, and limited control of industrial emissions. PM effects on blood pressure (BP) have been investigated as a mechanism mediating cardiovascular risks, but results have been inconsistent.
Methods The Beijing Truck Driver Air Pollution Study (BTDAS) was conducted shortly before the Beijing 2008 Olympic Games (June 15-July 27, 2008) and included 60 truck drivers and 60 office workers in Beijing. Personal PM2.5 measured during work hours using portable small-sized monitors and post-work BP measurements were obtained on two different days, separated by 1-2 weeks. We used ambient PM10 data averaged for the 5 days before the study from 27 monitoring stations operating in Beijing. Mixed-effect regression models were used to examine associations of exposures (group, PM2.5, or PM10) with BP controlling for age, gender, BMI, day of the week, smoking, pack-years and cigarette/day, work hours/week, tea, alcohol, and outdoor temperature.
Results. Mean personal PM2.5 was 94.6 µg/m3 (SD=64.9) in office workers and 126.8 (SD=68.8) in truck drivers (p<0.001). Systolic (SBP), Diastolic (DBP) and mean (MAP) BP was not different between the two groups (p>0.14). Also, personal PM2.5 during work hours was not associated with BP. In all subjects combined, a 10 μg/m3 increase in 5-day ambient PM10 was associated with BP increments equal to 0.63 (95%CI 0.09-1.16), 0.50 (95%CI 0.06-0.95), and 0.55 (95%CI 0.13-0.96) mmHg for SBP, DBP, and MAP, respectively.
Conclusions. Our study shows a delayed effect of ambient PM10 on BP. The absence of associations with the exposure group and with personal PM2.5 measured during work hours indicates that the PM10 effects are related to the background levels of particulate pollution in Beijing, rather than to traffic exposure.
- © 2011 by American Heart Association, Inc.