Abstract 15080: Six Year Outcomes Following Endovascular Therapy with Nitinol Stenting in the Femoropopliteal Artery: Retrospective Multicenter Analysis for stenting of FemoroPopliteal lesions.
Background: Treatment strategy for patients presenting with femoropopliteal artery (FP) lesions remains controversial. Recently, nitinol stenting in the FP lesions has yielded improved mid-term results. The purpose of this study was to investigate the long-term outcomes of nitinol stent implantation in FP lesions as long as 6 years and to determine the factors associated with the restenosis in FP lesions.
Method: Between December 2003 and December 2009, 784 patients with 996 FP lesions (mean age 72 years; 70% male) underwent nitinol stent implantation. Restenosis was defined either by duplex ultrasound (peak systolic velocity > 2.4), or angiography (>50%). Patency was analyzed by Kaplan-Meier estimation.
Results: Mean (±SD) length of the treated segments was 152±94mm. Stent fracture occurred in 10.6% of lesions. At 1, 2, 3, 4, 5, and 6 years, the primary patency rates were 77.9%, 70.4%, 65.6%, 62.6%, 58.7% and 56.1%; secondary patency rates, 92.8%, 89.0%, 87.4%, 85.5%, 83.2%, and 81.9%, respectively. By multivariable Cox regression analysis, female (hazard ratio [HR], 1.37; 95% confidence interval [CI], 1.07-1.75; P=0.014), reference vessel diameter (HR, 0.87; 95% CI, 0.76-0.99; P=0.037), and TransAtlantic Inter-Society Consensus (TASC) C or D lesion (HR, 1.81; 95% CI 1.22-2.70; P=0.003) were the strong independent factors associated with restenosis.
Conclusions: Endovascular therapy using nitinol stents for FP lesions yielded acceptable outcomes as long as 6 years.
- © 2011 by American Heart Association, Inc.