Abstract 14243: Risk of Cerebrovascular Events and Atrial Fibrillation After Typical Atrial Flutter Ablation
Introduction: There are a paucity of data on the incidence of and risk factors for cerebrovascular events (CVE) and atrial fibrillation (AF) after radiofrequency ablation of typical atrial flutter (AFl). This study sought to define the incidence of CVE and AF following typical AFl ablation and to identify potential factors that may increase long-term risk for CVE in this patient population.
Methods: All patients undergoing typical AFl ablation at a single center between 2002 and 2010 were included. Computerized records were available on all subjects and these were reviewed to determine demographics, baseline co-morbidities, and post-ablation outcomes, which included the incidence of AF and CVE.
Results: A total of 126 patients (age: 66+10 years, 100% male) were included in this study. The mean follow-up for this cohort after AFl ablation was 25±20 months. Over this follow-up, AF occurred in 46 (37%) patients, 26 (57%) of whom had previously documented AF. The incidence of new onset AF after AFl ablation was 120 cases per 1000 person-years. New CVEs occurred in 8 (6%) patients during this follow-up, resulting in an incidence of 30 CVEs per 1000 person-years. Six (75%) of the 8 patients with CVE had documented AF after ablation. The presence of AF after AFl ablation was the only risk factor that was significantly associated with incident CVE after ablation (see Table).
Conclusions: Despite successful ablation of typical AFl, these patients remain at an elevated risk for new onset AF and CVE. Since AF is the major identifiable risk factor for CVEs in these patients, minimizing the latter may require rigorous monitoring and / or prolonged anticoagulation post ablation.
- © 2011 by American Heart Association, Inc.