Abstract 13775: Pressure Gradient Can Select Good Responder After Renal Stenting
Background: The role of renal artery stenting is uncertain, particularly after the publication of the Angioplasty and Stenting for Renal Artery Lesions trial and other randomized trials. These trials have shown that nonselective treatment of patients with renal artery stenosis does not result in a benefit when compared with best medical therapy. However, all trials have identified a subgroup of patients who do respond favorably to revascularization. Thus it is important to find parameters which correlate with improvement of renal function after renal stenting. Therefore, in this study we investigated various factors which may correlate with renal function in the patients who underwent virtual histology intravascular ultrasound (VH-IVUS) guided renal stenting with distal protection (Filtrap).
Methods: We divided 26 consecutive patients with renal stenting into two groups: B group whose renal function improved after renal stenting (estimated glomerular filtration rate (GFR) one month after procedure > eGFR just before procedure) and W group whose renal function did not improve. We compared VH-IVUS parameters including plaque volume, necrotic core (NC) volume and incidence of NC, existence of material by Fitrap, pressure gradient before procedure, and incidence of hypertension, diabetes mellitus and dyslipidemia.
Results: As shown in a table, pressure gradient before procedure in group B was signifincantly higher than that in group W while the other parameters including VH-IVUS factors showed no significant differences between the two groups.
Conclusions: Pressure gradient may become a good predictor to select the patients who will receive the beneficial effects after renal stenting.
- © 2011 by American Heart Association, Inc.