Abstract 13480: Exercise Capacity and Risk for Heart Failure in Older Adults. The Health, Aging, and Body Composition Study
Background: Exercise capacity declines with aging. Reduced exercise capacity is associated with increased cardiovascular risk and mortality. However, data on exercise capacity and risk of heart failure (HF) are limited, especially in older adults.
Methods: We examined the association of long-distance corridor walk (LDCW) performance with 5-yr HF risk in 2576 participants of the Health ABC Study (age, 73.5±2.9 yrs; 51.6% women; 60.0% white; 40.0% black) who were HF-free at baseline. The LDCW is a 2-stage, self-paced test that helps older adults approach their maximum exercise capacity. The test consists of a 2-min warm-up walk followed by a 400-m walk in a 20-m hallway. We used proportional hazards models accounting for competing mortality to examine the association of LDCW parameters with incident HF; in adjusted models, we controlled for previously identified HF predictors in the Health ABC Study.
Results: The test was completed by 2245 (87.2%) participants. Non-completers had 75% higher (95% CI: 17% to 161%; P=0.006) 5-yr HF risk HF compared to completers. Table 1 summarizes LDCW performance in completers. The association of LDCW parameters with HF risk is summarized in Table 2. Both the initial 2-min and the 400-m performance parameters were strongly associated with HF risk in unadjusted models. In models adjusted for other HF risk factors, the initial 20-m speed was still associated with HF risk. There were no gender- or race-related interactions.
Conclusion: Reduced exercise capacity, assessed through a simple walk test, is associated with increased 5-yr HF risk in older adults. Whether exercise training may reduce HF risk in these individuals needs further investigation.
- © 2011 by American Heart Association, Inc.