Abstract 13451: Persistent Gender Disparities in Acute Myocardial Infarction Hospitalizations and Mortality by Age
Background: Cardiovascular disease remains the leading cause of morbidity and mortality for women in the United States. Although mortality rates for acute myocardial infarction (AMI) have declined for both men and women, prior studies have reported a gender gap in mortality, such that younger women (age <70) were most likely to die after an AMI. We sought to explore if the gender gap in AMI incidence and mortality has narrowed in a contemporary patient cohort.
Methods: Using nationally representative administrative data from the 2007 and 2008 Healthcare Cost and Utilization Project (HCUP), we constructed a hierarchical logistic model to examine trends in AMI hospitalizations and in-hospital mortality by both gender and age, adjusting for patient comorbidities.
Results: There were 151,672 AMI discharges for men and 102,292 discharges for women. The average age of index AMI admission for men was 64 (S.D. 14) and 71 (S.D. 14) for women; 30% of women and 51% of men were under age 65. Men had a significantly higher hospitalization rate for AMI at all ages, with the highest incidence in the 55-60 year age group (Figure). However, in-hospital mortality rates were higher for women under 65 (interaction term for AMI mortality and age: -0.006, p<0.001).
Conclusion: Despite overall reductions in AMI mortality for both men and women over the last decade, young and middle-aged women have higher in-hospital mortality compared with men. Continued efforts to reduce gender disparities in AMI mortality are needed.
- © 2011 by American Heart Association, Inc.