Abstract 13037: Age-Specific Stroke Trends from 1980 to 2000: The Minnesota Stroke Survey
Introduction: With an increasing prevalence of obesity and diabetes, two known risk factors for stroke, there is a need to re-evaluate age-specific stroke trends. We hypothesized increasing stroke rates in younger adults between 1980 and 2000.
Methods: The Minnesota Stroke Survey is a population-based surveillance study of acute stroke hospitalizations among Twin Cities residents (2000 census: 2.6 million). In each of the 5 surveys (1980, 1985, 1990, 1995, and 2000), strokes were identified from hospital discharge diagnoses, and data were collected via chart review. Stroke was defined using the World Health Organization (WHO) criteria. The study was restricted to patients aged 35-74 years, who were categorized into four 10-year age groups. Analysis of incident stroke was limited to the four most recent surveys. Sex-specific rates (per 100,000 population) were estimated and trends assessed using Poisson regression.
Results: Stroke trends differed across age groups in men between 1980 and 2000 (age group x time interaction: p=0.05)(Figure Part A). During this time, the stroke rate decreased in the 3 older age groups (p<0.0001 for all) but did not change substantially among those aged 35-44 years (p=0.28). This interaction was no longer significant when restricted to incident strokes between 1985 and 2000 (p=0.95). Among women, the WHO-defined stroke rate decreased in all age groups between 1980 and 2000 (p<0.0001 for all), with greater decreases observed in older age groups (p=0.0002)(Figure Part B). The incident stroke rate among women decreased in all age groups between 1985 and 2000 (p<0.05 for all), but differences across age groups were not significant (p=0.43).
Conclusion: Older women experienced a greater decrease in WHO-defined strokes than their younger counterparts in Minnesota between 1980 and 2000. In men, rates decreased between 1980 and 2000 among those in older age groups but did not change substantially among those aged 35-44 years.
- © 2011 by American Heart Association, Inc.