Abstract 12328: Differentiation Between Tachyccardia Induced Cardiomyopathy and Dilated Cardiomyopathy
Backgroud: The clinical manifestations of tachycardia-induced cardiomyopathy (TIC) and dilated cardiomyopathy (DCM) with tachyarrhythmia are similar. It is difficult to differentiate between them prior to treatment.
Objective: To clarify the differentiation of general clinical data between TIC and DCM.
Methods: We evaluated clinical data derived from 12-lead electrocardiography(ECG) during tachyarrhythmia, echocardiography, and 123I-metaiodobenzylguanidine (123I-MIBG) scintigraphy of 21 patients with TIC (TIC group, 60.3 ± 18.5 years, 11 males) and 24 patients with DCM (DCM group 51.7 ± 18.6 years, 21 males).
Results: The ejection fraction (EF) prior to treatment was similar in both groups. However, the EF of the TIC group improved from 37.3 ± 11.4% to 53.5 ± 7.7% after treatment, while that of the DCM group did not improve. The left ventricular diastolic and systolic dimensions (LVDd&LVDs) were smaller in the TIC group than that in the DCM group (LVDd 51.7 ± 6.7 mm vs 63.3 ± 9.0 mm, LVDs 40.8 ± 7.4 mm vs 53.6 ± 10.1 mm, P < 0.05). The QRS duration in aVR lead during tachycardia was longer in the DCM group than that in the TIC group (0.094 ± 0.014 ms vs 0.074 ± 0.011 ms, P < 0.05). Additionally, R-wave/S-wave ratio in aVR lead (R/S) was smaller in the TIC group than that in the DCM group (0.033±0.021 vs 0.064±0.013, P<0.05).The washout ratio of 123I-MIBG scintigraphy was higher in the DCM group than that in the TIC group (55.5 ± 14.7% vs 31.4 ± 8.1%, P < 0.05).
Conclusion: LVD at initial echocardiography, QRS duration and R/S in lead aVR, and the washout ratio may be useful in differentiating TIC from DCM in patients with left ventricular dysfunction and tachyarrhythmia.
- © 2011 by American Heart Association, Inc.