Abstract 12007: Prophylactic Catheter Ablation Before Cardioverter Defibrillator Implantation Can Prolong the Time to First Shock Therapy and Electrical Storm in Patients with Sustained Ventricular Tachycardia and Non-Ischemic Cardiomyopathy
Background: Prophylactic ventricular tachycardia (VT) ablation before cardioverter defibrillator implantation in patients with stable VT and ischemic cardiomyopathy (ICM) prolongs time to recurrence of VT, but that in patients with non-ischemic cardiomyopathy (NICM) is unknown.
Purpose: We assessed the efficacy of prophylactic catheter ablation in patients with NICM.
Methods: 80 consecutive patients with sustained VT and NICM, received intervention with an implantable cardioverter defibrillator (ICD), were assessed retrospectively. We compared the clinical outcome in patients undergoing successful VT ablation before ICD (ABL group) with that in patients undergoing ICD alone (ICD group). Successful ablation was defined as non-inducibility of clinical VT by extra double stimuli of right ventricle. The endpoint was appropriate ICD therapy (shock and anti-tachycardia pacing).
Results: Mean follow-up was 988.42±541.11days. NICM were dilated cardiomyopathy, cardiac sarcoidosis, arrhythmogenic right ventricular cardiomyopathy, hypertrophic cardiomyopathy, Valvular heart disease and others. VT ablation was performed in 36 of 80 patients and succeeded in 17. The time to first appropriate shock therapy and electrical storm was significantly longer in ABL group than ICD group (p=0.0302, p=0.0472).
Conclusion: Prophylactic catheter ablation was able to prolong time to first shock therapy and ES in patients with NICM. It may improve the quality-of-life even in the patients with NICM.
- © 2011 by American Heart Association, Inc.