Abstract 11953: Global Circumferential Strain from Routine Cardiac Magnetic Resonance Image Analysis Using a Novel Off-Line Approach: Comparison with Echocardiographic Strain and Left Ventricular Ejection Fraction
Background: Cardiac magnetic resonance (CMR) imaging is considered the gold standard for left ventricular (LV) strain and ejection fraction (EF). However, strain by CMR tagging is complex and time-consuming. Our aim was to utilize a novel rapid off-line software approach using CMR DICOM images to determine global circumferential strain (GCS), global longitudinal strain (GLS) in comparison to LVEF and similar echocardiographic measures in the same patients.
Methods: We studied 50 consecutive patients, aged 53±15 yrs who had both CMR and echocardiography (echo). Routine DICOM CMR images data sets were analyzed using a novel software program (Image-Arena VA, TomTec, Corp). GCS was the average of the regional peak circumferential strain in the six myocardial segments of mid-LV short axis and GLS was calculated as the average all 18 regional peak longitudinal strain in the standard apical 3 views. They were compared with similar short axis echo images for speckle tracking circumferential strain (Image-Arena, TomTec, Corp). CMR EF was measured using conventional software (Argus, Siemens) from multiple short-axis images.
Results: CMR-GCS was strongly correlated with CMR EF (r=0.90, p<0.0001) as was CMR-GLS (r=0.89, p<0.0001). Also echo-GCS correlated with CMR EF (r = 0.83, p<0.0001) more so than echo-GLS (r=0.71, p<0.0001). CMR-GCS and echo-GCS had very good correlation (r=0.81, p<0.0001) and CMR-GLS and echo-GLS also had fair, but significant correlation (r=0.67, p<0.0001).
Conclusions: This novel semi-automated method could rapidly quantify strain using routine CMR images. CMR-GCS had an excellent correlation with CMR EF, and was more closely correlated that echo-GCS or echo-GLS with CMR EF. CMR strain imaging using this new simplified approach has promise for the clinical evaluation of LV systolic function.
- © 2011 by American Heart Association, Inc.