Abstract 11723: Six-Minute Walk Distance is an Independent Predictor for Rehospitalization in Patients with Chronic Heart Failure
Background: Patients with chronic heart failure (CHF) are well known to enter the hospital repeatedly because of the deterioration of CHF. The 6-minute walk distance (6MWD) is reported as one of the prognostic factors, less than 300 meters of which indicate a high mortality and morbidity in them.
Purpose: To investigate whether or not a 6MWD measured at the hospital discharge predicts the rehospitalization in patients with CHF.
Methods: We studied 240 patients (156 males and 84 females, 68.5 ± 11.3 years) who entered the hospital because of initial heart failure. They were followed up for 3 years, after clinical characteristics, plasma brain natriuretic peptide, left ventricular ejection fraction (LVEF), 6MWD and motor function were assessed at the hospital discharge. The cut-off value of 6MWD for the rehospitalization was analyzed using logistic regression analysis and receiver-operating characteristics (ROC) curve.
Results: Of 240 patients, 97 were rehospitalized within a 3-year follow-up period. The univariate logistic regression analysis showed that the 6MWD, age and LVEF were significant predictors for the rehospitalization (P<0.001, P<0.01 and P<0.05, respectively). Furthermore, the multivariate logistic regression analysis showed that the 6MWD was significant and independent predictor for the rehospitalization (odds ratio: 1.021, 95% confidence interval: 1.015-1.027, P<0.001). The 6MWD of ≤390 meters was detected by the ROC curve as the cut-off value (Figure), indicating that the probability of rehospitalization was 11.068-fold higher in patients showing 6MWD of ≤390 meters than in those doing 6MWD of >390 meters (P<0.001).
Conclusions: The 6MWD was identified as strong predictor for the rehospitalization, and the 6MWD of >390 meters was necessary to avoid it in patients with CHF.
- © 2011 by American Heart Association, Inc.