Abstract 11216: Reproducibility and Interobserver Agreement of Global Longitudinal Strain between Novice and Expert during Dobutamine Stress Echocardiography
Background: Wall motion analysis (WMA) during dobutamine stress echocardiography (DSE) is subjective and requires expert training. Global longitudinal strain (GLS) has been shown to have incremental value to WMA to detect myocardial ischemia. However, the reproducibility of GLS during DSE remains unclear.
Aim: To determine the interobserver agreement of GLS between novice and expert readers during DSE.
Methods: Twenty four patients (age 67±14 years, ejection fraction (EF) 58±12%) underwent DSE as per clinical protocol. Images were acquired using Vivid E9 (GE-Vingmed, Horten, Norway) at rest, low dose, and peak dose dobutamine infusion. Offline analysis was performed using EchoPAC BT09, GE-Vingmed. GLS was measured by two independent, blinded observers. Other parameters included EF, wall motion score index (WMSI) and number of dysfunctional segments (DS). Statistical analysis was performed using Bland Altman analysis (mean differences±2 SD) and Pearson's correlation (r).
Results: Interobserver agreement for GLS is represented in the table 1. Correlation of GLS with other parameters is shown in the table 2.
Conclusions: GLS measurements were highly reproducible during DSE with excellent interobserver correlation between expert and novice readers. There was good correlation of GLS with EF, WMSI, and DS during all stages of DSE. GLS is a potential reliable and reproducible quantitative parameter for DSE.
- © 2011 by American Heart Association, Inc.