Abstract 10258: Impact of Carotid Artery Intima-Media Thickness and Ankle-brachial Index for Prediction of the Severity of the Syntax Score
Purpose: Numerous reports showed that carotid artery ultrasound (carotid-US) findings or ankle-brachial index (ABI) have relationship with the presence of coronary artery disease. However, most of them did not assess about the complexity of the coronary artery disease. Recently, the SYNTAX score (SX score) representing a lesion complexity has been to be useful for long-term prognosis. We aimed to examine the relationship between carotid-US findings or ABI and severity of the SX score.
Methods: Subjects were 496 consecutive patients who underwent carotid-US, ABI and first coronary angiography from December 2008 to January 2011. In carotid-US, mean common carotid artery intima-media thickness (mean-CCA-IMT) was evaluated. The lowest ABI obtained for either leg was taken as the ABI measurement for the patients.
Results: Patients with carotid intima-media thickening (mean-CCA-IMT≥0.9mm) showed significantly higher SX score than the patients without thickening (mean CCA-IMT< 0.9mm) (13.3±18.1 vs 3.2±6.8, p< 0.0001). Similarly, the patients with low ABI (< 0.9) presented significantly higher SYNTAX score than the patients with ABI≥ 0.9 (18.2±19.6 vs 7.4±13.7, p< 0.0001). When the patients were divided into 4 groups (Group-A: mean-CCA-IMT< 0.9mm, ABI≥ 0.9, Group-B: mean-CCA-IMT< 0.9mm, low ABI, Group-C: mean-CCA-IMT≥ 0.9mm, ABI≥ 0.9, Group-D: mean-CCA-IMT≥ 0.9mm, low ABI ), the SX score of the groups presented significant difference (Group-A:3.0±6.5, Group-B: 6.6±9.9, Group-C: 11.4±17.0, Group-D: 21.8±20.6, p< 0.0001). Among the patients of Group-D (n=48), 75% had coronary artery disease (SX score was not 0).
Conclusions: Carotid-US and ABI findings are associated with the SYNTAX score, respectively. The combination of the carotid-US and ABI provide useful information to predict the complexity and presence of coronary artery disease.
- © 2011 by American Heart Association, Inc.