In the article by Norrmén et al, “Biological Basis of Therapeutic Lymphangiogenesis,” which published in the March 29, 2011 issue of the journal (Circulation. 2011;123:1335–1351), the authors included an outdated view on fluid balance in the microcirculation. In the second paragraph of their article, the sentence:
“Most of the extravasated interstitial fluid is absorbed back by colloid osmotic pressure into the blood capillaries on the venous side of the capillary bed, while the remaining fluid and macromolecules are taken up by the lymphatic vessels (Figure 1).”
Has been revised to state the following:
“Most of the extravasated interstitial fluid and macromolecules are absorbed back by the lymphatic vessels, whereas some reabsorption may also occur in the venules, depending on the tissue (Figure 1).”
Figure 1 has also been replaced to reflect this correction. The correct figure appears as follows:
The Legend to Figure 1 has also been updated and now reads:
Reference 1, which is cited in the Figure legend, has also been updated. It now refers to:
Lick JR, Michel CC. Microvascular fluid exchange and the revised starling principle. Cardiovasc Res. 2010;87:198–210.
These changes have been made to the current online version of the manuscript. The authors regret the errors.
- © 2011 American Heart Association, Inc.