Abstract 9386: Non-invasive Assessment Of Atherosclerotic Coronary Lesion Length Using Multidetector Computed Tomography Angiography: Comparison To Quantitative Coronary Angiography
Background: Coronary multidetector computed tomography angiography (CTA) is able to provide valuable information on atherosclerotic plaque extent in the coronary arterial wall, in addition to assessment of luminal narrowing. Potentially, more accurate atherosclerotic lesion length assessment may be feasible with CTA as compared to invasive coronary angiography (ICA). Objectives: To compare lesion length assessment between ICA and CTA in patients undergoing percutaneous coronary intervention (PCI).
Methods and Results: In total, 89 patients underwent CTA prior to ICA and PCI. On CTA, plaque was defined as a structure ≥1mm2 in the coronary artery lumen. Lesion length was measured from the proximal to distal shoulder of the plaque. Quantitative coronary angiography (QCA) was performed to analyze target lesion length. Stent length was recorded for each lesion treated. In total, 119 lesions were identified that had undergone PCI subsequent to CTA imaging. Mean lesion length on CTA was 21.4±8.4mm. Mean lesion length on QCA was 12.6±6.1mm and mean stent length deployed was 17.4±5.3mm. The mean difference between CTA and QCA lesion length was 8.9±6.72mm whereas the difference between stent length and QCA was 4.8±6.2mm. Lesion length on CTA was significantly longer than on QCA (p<0.001).
Conclusion: Our study shows that lesion length assessed by CTA is substantially longer than lesion length assessed by ICA. Possibly, CTA may provide more accurate lesion length assessment than ICA and may facilitate improved guidance of percutaneous treatment of coronary lesions.
- © 2010 by American Heart Association, Inc.