Abstract 9220: Coronary Wall MR imaging In Patients With Rapid Heart Rates: A Feasibility Study Of Black-blood Steady-state Free Precession (ssfp)
Background: The turbo (fast) spin echo (TSE, FSE) magnetic resonance (MR) imaging has been used for detecting atherosclerosis on coronary wall. However, TSE is sensitive to cardiac motion (related to heart rate). Such a characteristic impedes its routine clinical application. We assessed the hypothesis that black-blood steady-state free precession (SSFP) would provide coronary wall images comparable to images from TSE and have better performance than TSE under conditions of fast heart rate.
Methods: Twenty six participants without a history of coronary artery disease (17 men, 9 women, 26–83 y/o) were scanned with a 1.5 T MR scanner. Cross-sectional black—blood images of the proximal portions of the right coronary, left main, and left anterior descending artery were acquired with a two-dimensional (2D), double inversion recovery (DIR) prepared TSE sequence and a 2D DIR SSFP sequence on the same planes. Image quality (ranked with a 4-point system, scored from 0–3), vessel wall area and thickness, signal-to-noise ratio (SNR) of the wall and contrast-to-noise ratio (CNR, wall to lumen) were compared between SSFP and TSE with SPSS software.
Results: Twenty four scans were completed. For SSFP and TSE, there was no difference in image quality (scores 1.66±0.86 vs. 1.65±0.89, P=0.890). Good agreement between measurements of wall area (r=0.776, P<0.001) and thickness (r=0.540, P<0.001), was found. SSFP had a higher SNR (23.7±9.3 vs. 14.1±5.0, P<0.001) and CNR (8.9±4.3 vs. 6.8±3.1, P=0.001) than TSE. For 7 participants with heart rate more than 80 beats/min, the image quality of SSFP was higher than TSE (1.38±1.02 vs. 0.85±0.72, P=0.004).
Conclusion: As an eligible option for coronary wall imaging, SSFP provides image quality and measurement accuracy that is comparable to TSE. With its better performance in patients with a high heart rate, SSFP may break through existing heart rate limits and potentially extend the applicability of coronary wall MR imaging to a larger population.
- © 2010 by American Heart Association, Inc.