Abstract 9205: Quantification of Left Ventricular Volumes and Longitudinal Strain Using 3-Dimensional Speckle Tracking Imaging: An In Vitro Validation Study
Background: Accurate quantification of left ventricular (LV) volumes are important in clinical cardiology. Our goal was to evaluate the accuracy of a new 3-dimensional (3D) speckle tracking imaging (STI) methods for LV volumes.
Methods: Seven freshly harvested pig hearts were studied on a model in a water bath designed to simulate filling and emptying. Five stroke volumes (SV; 20, 40, 60, 80, 100ml) were studied at a constant heart rate of 60 beats/min. To maintain a constant LV end-systolic volume, we added 20ml water into pump system with every 20ml SV increase. Full volume 3D image loops were acquired on a Toshiba Applio® Artida® system at maximized frame rates. Images were analyzed on the system with WMT software for 3D volumes analysis.
Results: With the pumping SVs increasing, the SVs and longitudinal strain (LS) by 3D STI also increased (20ml: SV, 21.41 ± 5.06ml; LS, 12.5 ± 14.%. 40ml: SV, 42.47 ± 6.57ml; LS, 15.5 ± 1.85%. 60ml: SV, 54.51 ± 5.52ml; LS, 18.75 ± 2.15%. 80ml: SV, 67.87 ± 4.15ml; LS, 19.15 ± 1.15%. 100ml: SV, 85.07 ± 10.45ml; LS, 22.15 ± 4.5%). All of the computed SVs and LS values had a strong correction with the pumping SVs (r = 0.956 and 0.727, respectively).
Conclusion: The new 3D STI program can calculate LV volumes and stroke volumes very well.
- © 2010 by American Heart Association, Inc.