Abstract 9052: A Validation Study of Right Ventricular Stroke Volume Determination by 3D Echocardiography
Background: The volume of the right ventricle (RV) is difficult to evaluate due to its inherent geometry. This study aimed to validate the accuracy as well as the precision of cavity volume and stroke volume (SV) determination of the RV using 3-dimensional (3D) echocardiography.
Methods: Balloons were inserted into both the RV and left ventricle (LV) of five dissected pig hearts. The initial volume of each ventricle was measured before being connected to a pulsatile pump; the LV was filled and fixed to distort the RV shape during distension, and the RV was connected to the pump, at SVs from 30–;50 ml in increments of 5 ml. 3D images were obtained using a Philips iE-33 system with an X7-2 transducer. The images were then analyzed using semiautomated 3D volume tracing software QLab 6.2 and compared to the actual values obtained from the measured stroke volumes.
Results: The linear regression showed excellent correlation between the 3D method derived SV and the reference data (y = 0.98x + 0.54, r = 0.98, p<0.001). There was also very good agreement between these two methods using the Bland-Altman method.
Conclusions: This newly developed QLab 6.2 software demonstrated reliability and feasibility for quantifying the complicated RV structure. It has great potential for future clinical evaluation of ventricular volume.
- © 2010 by American Heart Association, Inc.