Abstract 291: Efficacy Of Air-Way Pressure Release Ventilation in Patients With Emergent Percutaneous Cardiopulmonary Support
Background: A proposed advantage of air-way pressure release ventilation (APRV) compared to conventional pressure-controlled ventilation is the improved distribution of gas to dependent lung regions. Therefore APRV is considered as an alternative “open lung approach” to conventional ventilation. In patients with percutaneous cardiopulmonary support (PCPS), oxygenations using only PCPS were insufficient occasionally, because of severe lung disorder and pulmonary congestion. We evaluated early outcome and conducted this study to determine the efficacy of APRV for PCPS weaning and hospital discharge.
Methods: From January 2006 to December 2009, 40 patients diagnosed as cardiac failure underwent PCPS using the Capiox emergent bypass system. The respirator modes were selected to conventional pressure-controlled ventilation in 20 Patients (Group I). APRV were selected in 20 patients (Group II).
Results: The patients' characteristics were similar in the two groups. The mean durations of PCPS and that of cardiopulmonary resuscitation (CPR) were no significant different in each groups. The implementations of mild therapeutic hypothermia (MTH) were similar in the two groups. The rate of weaning PCPS was 11/20 (55%) in Group I, although it was 17/20 (85%) in Group II (P<0.05). The rate of survival to discharge were no significant differences in each groups (Group I; 45% v.s. Group II; 60%).
Conclusions: The ventilation mode of APRV increases the success rate of weaning PCPS. APRV might be new recommended mode of ventilation in patients with cardiac support.
- © 2010 by American Heart Association, Inc.