Abstract 270: Assessment of the Benefit of Extracorporeal Life-Support for Patients With Cardiac Arrest in Terms of Cerebral Oxygen Saturation.
Background: Near infrared spectroscopy (NIRS) is an easily applied and a noninvasive technique that provides continuous monitoring of regional cerebral oxygen saturation (rSO2). rSO2 has also been found helpful in the prognosis of outcome after cardiac arrest (CA). Extracorporeal life-support as an adjunct to cardiac resuscitation has shown encouraging outcomes in patients with CA. However, there is little evidence about the benefit of procedures comparing conventional cardiopulmonary resuscitation (CPR).
Objective: We aimed to assess whether extracorporeal CPR was better than conventional CPR for patients with CA to maintain higher rSO2.
Methods: We did a prospective observational study. We included adults with out-of-hospital CA who underwent CPR and achieved recovery of spontaneous circulation (ROSC). We compared with patients who received only conventional CPR and those who received conventional and extracorporeal CPR. rSO2 was measured during all through conventional and extracorporeal CPR, and after ROSC in all patients by NIRS (TOS96, Tostec, Tokyo, Japan).
Results: Of the 9 patients with out-of-hospital CA who underwent CPR and achieved recovery of spontaneous circulation, 6 were received conventional CPR (group A) and 3 were received extracorporeal CPR (group B). In Group A, all patents got higher rSO2 after ROSC. (41.2±19.3% vs 47.6±15.0%, respectively) In Group B, all patients got higher rSO2 after beginning of extracorporeal CPR. (53.6±5.7% vs 64.3±5.9%, respectively) rSO2 in patients receiving extracorporeal CPR (n=3) was as high as in patients after ROSC (n=9). (64.3±5.9% vs 53.2±14.9%, respectively) (mean±SD)
Conclusion: This study suggests that extracorporeal CPR may improve rSO2 in patients with out-of-hospital CA and their neurological outcome. These results are preliminary. Further studies are needed.
- © 2010 by American Heart Association, Inc.