Abstract 230: A Marker of Resuscitation Outcome in Patients Who Were Treated With Extracorporeal Cardiopulmonary Resuscitation After Out-of-Hospital Cardiac Arrest Failed.
Backgraund: Since 1996, we performed E-CPR (PCPS, coronary reperfusion therapy and hypothermia) in patients who arrived at the ER in cardiac arrest and failed to respond to standard CPR. However, few studies of echogram were available for resuscitation outcome.
Methods: A total of 40 patients treated with E-CPR were enrolled in this prospective study. Using echogram, cardiac function (CI, LVSVI, LVEF, EDVI, aortic valve ejection time (AVET)) for cardiac resuscitation and common carotid artery (CCA) flow for cerebral resuscitation were investigated according to our E-CPR protocol.
Results: Of the 40 patients, 19 (48%) were weaned from PCPS successfully, and 4 (10%) had a favorable neurological outcome at 30 days after out-of-hospital cardiac arrest. At the time of PCPS flow of 3.0 l/min, Succeeded PCPS weaning group was higher levels of AVET than failed PCPS weaning group (AVET 181.62 vs 61.47, p<0.0001). The AVET cut off value of 106.5msec for PCPS weaning. The favorable recovery group was a higher level of CCA flow than the unfavorable group (375.9 vs 168.0 p=0.0002). The CCA flow cut off value of 173ml/min for a favorable neurological outcome.
Conclusions: In patients who were treated with E-CPR, echogram findings at the time of PCPS flow of 3.0ml/min were a useful marker of resuscitation, especially CCA flow of 173ml/min or more was associated with improvement of a favorable neurological outcome.
- © 2010 by American Heart Association, Inc.