Abstract 219: Feasibility and Quality of Rapid Standard EEG Testing in Post Cardiac Arrest Patients
Background: The availability of an objective method to assess ongoing neurologic injury, diagnose evolving neuropathology (e.g. seizures), establish prognosis and track neurological status in the early recovery period after cardiac arrest could lead to better clinical management of the patient. In this study, we sought to demonstrate the feasibility of performing early EEGs in post-cardiac arrest patients.
Methods: After obtaining informed consent, we performed 30-minute standard montage EEGs on patients resuscitated from cardiac arrest as close to the time of return of spontaneous circulation (ROSC) as clinically allowable at all times and days of the week as part of a multicenter trial. Therapeutic hypothermia data and medical events were recorded. An investigator blinded to the clinical conditions evaluated the EEG data for quality (1 (excellent) — 4 (unusable)).
Results: Standard, early, EEG was performed in 52 patients and 41 had therapeutic hypothermia. The mean time from ROSC to EEG was 5.42 ± 1.6 hours (IQR: 4.17 – 6.42 hours), and there was no difference in time to EEG between in-hospital and out-of-hospital arrests and hypothermia and non-hypothermia treated subjects. Fifteen subjects had cardiac interventions and had similar ROSC-to-EEG times compared to those without interventions. Eighty-two percent of hypothermia patients and 83% of non-hypothermia patients had excellent or good quality (1–2) EEG recordings. The mean overall EEG quality score was 1.72.
Conclusions: Early standard EEG testing in post-cardiac arrest patients is feasible and high quality. Emergent care, coronary intervention and therapeutic hypothermia did not inhibit early EEG testing in the ICU. Early EEG did not delay interventions. This study provides feasibility for performing a larger post-cardiac arrest EEG study.
- © 2010 by American Heart Association, Inc.